Prof (MD) David Systrom
Brigham and Women's Hospital and Harvard Medical School, Boston, USA
Website Presentations
Low-dose Naltrexone (LDN) and Mestinon trial in ME/CFS
Circulatory dysfunction in ME/CFS
Chair
Session: Understanding I: Cardiovascular dysregulation and mitochondrial pathology
Prof David Systrom is an Assistant Professor of Medicine at Brigham and Women’s Hospital and the director of the Massachusetts General Hospital Cardiopulmonary Laboratory in Boston, USA. Prof Systrom is also an Assistant Professor of Medicine at Harvard Medical School where he directs the Dyspnea Clinic and the Advanced Cardiopulmonary Exercise Testing Program. For more than 10 years he has been using invasive cardiopulmonary exercise testing (CPET) to investigate mechanisms underlying fatigue, shortness of breath and orthostatic intolerance in ME/CFS and recently also Long COVID/post-COVID syndrome. His recent work suggests commonality between the two, in particular neurovascular dysregulation and related hyperventilation underlying symptoms during exercise. Prof Systrom is the principal investigator of several ongoing clinical studies, including on limb skeletal muscle mitochondrial dysfunction as well as of clinical trials investigating pharmaceutical treatments for ME/CFS, implemented with the support of the Open Medicine Foundation (OMF).
