BMBF-Forschungsverbund: BioSig-PEM - Identifizierung biopathologischer Signaturen von Post-Exertional Malaise bei ME/CFS

Prof Christian Puta outlined the work of the "Identification of biopathological signatures of post-exertional malaise in ME/CFS (BioSig-PEM)" research network. It network aims to investigate the cardinal symptom of ME/CFS, the stress-related worsening of symptoms in the form of Post-Exertional Malaise (PEM). Via 6 sub-projects, the overall goal is to identify central pathophysiological signatures of PEM phenotypes in ME/CFS patients with the help of fitness trackers, molecular and immunological as well as imaging methods. This work is expected to make an important contribution to a better understanding of the pathophysiology of ME/CFS and to help measure the severity of individual PEM phenotypes. This will contribute to the development of new diagnostic and therapeutic approaches based on disease progression in the future.