BMBF-Forschungsverbund: SERIMM - Serotonin und Immunmodulation in ME/CFS

Dr Helena Radbruch presented the "Serotonin and immunomodulation in ME/CFS (SERIMM)" research network, which aims to shed light on evidence of an altered metabolism of the neurotransmitter serotonin and a dysregulation of the immune system. To this end, the network's five sub-projects, will use high-throughput analysis methods to examine samples from patient cohorts and COVID-19 animal models (mice, hamster) in parallel. This work is intended to make an important contribution to a better understanding of the pathophysiology of ME/CFS and help to better understand changes in the tissue and immune system in ME/CFS. Furthermore, ME/CFS-specific biomarkers may be discovered and mechanistic studies will be conducted in animal models. This will allow the testing of drugs and other treatment modalities for ME/CFS in preclinical models in the future and is hoped to contribute to the development of new therapeutic approaches.